Why Bone Marrow Stem Cells are Superior to other stem cellsJune 14, 2018 June 14, 2018
Stem cells are the basic building blocks of the body and are highly beneficial to treat many serious disorders. Stem cells can be harvested from different parts of the body. Bone marrow-derived stem cells are known to be better than other types of stem cells. Research shows that bone marrow includes cells that can generate connective tissue forming cells. Bone marrow stromal cells are also known as multipotential stromal cells or mesenchymal stem cells.
Bone marrow is a sponge-like soft tissue situated within the hollow interior of long bones. Healthy blood cells and healthy bone marrow are essential to health. When disorders affect bone marrow, it is not able to function properly. In that case, cord blood or a marrow transplant is the best treatment option. Bone marrow has the largest concentration of blood stem cells. The procedure used to collect bone marrow stem cells is called bone marrow harvest.
Bone marrow stem cells are most useful in:
Treatment of blood diseases
Repairing brain damage
Treatment of autoimmune diseases
Red bone marrow contains highly delicate, vascular fibrous tissue containing hematopoietic stem cells. Yellow bone marrow contains mesenchymal stem cells that produce bone, cartilage, and fat. Bone marrow-derived stem cells are currently utilized in numerous clinical trials to determine their potential in tissue generation, hematopoiesis or immune regulation. Bone marrow contains many different types of cells including blood stem cells and a variety of cells belonging to a group called mesenchymal cells.
Mesenchymal stem cells are useful for regeneration and repair of a variety of mesenchymal tissues such as marrow stroma, muscle, cartilage, bone. Mesenchymal stem cells produce cytokines and useful growth factors that may help repair additional tissues. Scientists are conducting research on how mesenchymal stem cells could be used to treat cartilage and bone diseases. Mesenchymal stem cells are multipotent stem cells found in bone marrow that are essential for repairing and generating skeletal tissues.
Mesenchymal stem cells make a very small fraction of all the cells in our bone marrow. Recent studies show that mesenchymal stem cells are important for creating home for blood stem cells in bone marrow. Mesenchymal stem cells can help recover from knee injuries or long-term accumulated damage that leads to osteoarthritis. They also help new blood vessels to form in damaged tissue.
Adult bone marrow-derived mesenchymal stem cells are able to differentiate along several lineages. Stroma of bone marrow contains mesenchymal stem cells which are extremely valuable in disease research. Bone marrow also contains progenitor cells which are useful for researchers to understand the root cause of autoimmune and blood disease. Adult bone marrow stem cells can also be used in actual patient treatments to treat a variety of serious conditions.
Mesenchymal stem cells usually reside in the bone marrow. These cells can differentiate into specialized cells of bone and cartilage. Researchers continue to examine the ability of mesenchymal stem cells to prevent transplant rejection. It also helps to slow down the progression of the autoimmune disease and to reduce inflammation.