stem-cells & bone marrow transplant

At the Basic: Stem Cell And Bone Marrow Transplant

Category: Blog

While pain is the worst for patients, it can be very unpleasant for the family as well.

Stem cell and bone marrow transplants can be the solution. With a long list of problems that it can solve everyone stands a chance of living a better life.

Bone marrow stem cell therapy can help patients suffering from:

  • Degenerative Joint Disease
  • Knee Pain (Arthritis, Osteoarthritis, Injury)
  • Immune System Disorders
  • Bone and Corneal Injuries
  • Blood Disorders
  • Muscle Tissue Injury
  • Tendon Tear
  • Spinal Cord Injury
  • Joint Pain
  • Tendinitis
  • Ligament Tears

Reading such a list won’t help. Acquiring a certain amount of knowledge on the treatments is crucial.

Read along to become familiar with the transplants. Who knows, you might be able to guide someone in the right direction.

Stem Cell Transplant

The procedure through which the patient’s cells that have been destroyed by disease, radiation, or high doses of anti-cancer drugs, are replaced with healthy blood-forming cells is known as the Stem Cell Transplant.

The healthy stem cells may be collected from the blood or bone marrow of the patient, a donor, or the umbilical cord of a newborn.

The adipose tissue is an exceptional source for collecting stem cells. It stores energy whilst insulating the body. The tissue is found beneath the skin, and around the internal organs as well.

Stem cells are versatile cells that have the ability to divide and develop into different kinds of cells. Hematopoietic stem cells produce 3 main components namely:

  • Red Blood Cells- They contain hemoglobin which carries oxygen around the body.
  • White Blood Cells- They are a part of the immune system, helping the body fight infection.
  • Platelets- They help cloth the blood, preventing excessive bleeding from a wound.

Stem cells are injected into the bloodstream through a tube called Central Venous Catheter. Think about it as getting a blood transfusion. Through the bloodstream, stem cells travel to the bone marrow. Here, the production of healthy stem cells can begin again.

There are 4 main types of stem cells that are found in our body:

  • Amniotic fluid and cord blood
  • Non-Embryonic
  • Induced Pluripotent Stem Cells
  • Embryonic

Bone Marrow Transplant

The procedure through which damaged or destroyed bone marrow is replaced with healthy bone marrow stem cells is recognized as a Bone Marrow Transplant.
The bone marrow is a soft, fatty tissue inside the bones that produces blood cells.
Bone marrow is generally collected from the larger bones found in the body i.e. the ribcage bones, the hip bone, and the breast bone.

The reason bone marrow is used to collect stem cells is that it contains special kinds of cells known as progenitor cells. These cells can grow new cartilage, tendons, and bones in the body. As they work towards regenerating the tissues, they produce chemicals that help reduce inflammation.

Mainly, there are 3 types of bone marrow transplants:

  • Autologous- Stem cells are removed from the patient before receiving any kind of treatment. The cells are stored in the freezer for future use. Once the treatment comes to an end, the stem cells are injected back into the body to start making normal blood cells. It is also known as a rescue transplant.
  • Allogeneic- Stem cells are removed from a donor. In most cases, the donor’s genes partly match with the patient’s genes. A blood relative tends to be the best match. Tests have revealed that at times, strangers have matched the genes criteria. Such donors could be found from online registries.
  • Umbilical- As the name suggests, stem cells are removed from the umbilical cord of a newborn right at birth. These cells are stored frozen until they are needed for a transplant. With umbilical stem cells, a perfect match isn’t required since they are immature.

A bone marrow transplant is required when there is a defect in the bone marrow because of which the production of blood cells is reduced. A decrease in the production of stem cells can make a person sick, cause pain, or even lead to a slow death. At times, abnormal amounts of stem cells are produced which is equally harmful to the patient.

The bone marrow stem cells knee therapy will help in treating the patient by replacing the cells that are not being produced with cells that are healthy.

Stem Cell Transplant For Knees

Knee pain affects millions of people and is an extremely common condition. It can have lasting effects on the physical and mental health of the person suffering from such pains.

With the advancements in regenerative medicine, doctors have been able to treat pain for a longer time and it has become cost-effective. It holds the power to make knee pain a thing of the past.

Before diving into the regenerative medicine here’s a little information about stem cell therapy for knees.

People have caught onto what osteoarthritis is, but here’s what this degenerative disorder is really about.

Osteoarthritis causes the joint cartilage to deteriorate over time due to injury, ligament tear, tendon damage, or a fracture.

When damaged, joints become unstable wearing down the articular cartilage. Because of this, the bone can suffer damage as well.

Stem cell transplant for knees is minimally invasive. It decreases inflammation, reduces damage from arthritis, and delays the chance of knee replacement surgery.

Matured stem cells have the ability to differentiate into cartilage, bone, fat, or soft tissue. Fat derived stem cells are found in abundance in bone marrow. These cells don’t decrease in number with age. Considerable improvement have been seen in patients dealing with knee pain. Stem cells can rebuild tissues and speed up the healing process.

At the doctor’s clinic, a sample of tissue is drawn from a specific part of the body. It depends on the doctor if the patient needs to be put under anesthesia or not. That is how mild the pain is. The collected tissue is inserted into the knee where stem cells get to work on the healing. In most cases, patients don’t feel pain even after the procedure.

At times growth hormones are introduced into the area where bone marrow stem cells knee therapy has been performed. These hormones let the body know that it needs to deliver blood, oxygen, and other nutrients to the area. This helps the stem cells thrive and the body repairs itself.

Research shows that stem cells might:

  • Develop into needed cartilage cells.
  • Suppress cartilage that can make knee pain worse.
  • Releases cytokines that slow down or in some cases decrease the pain.

Since the cells are collected from the patient, the risk of rejection reduces and the chances of healing increase.

Tests Performed

Before the bone marrow transplant or stem cell transplant can be initiated, doctors perform certain tests, including:

  • Blood tests and tissue typing
  • Pulmonary function test
  • CT or CAT scans
  • Bone marrow biopsy
  • Skeletal survey
  • Heart function tests

Various other precautions will also be taken to ensure the wellbeing of the patient.

Blood vessels around the bone marrow prevent immature cells from leaving the bone marrow. Only the mature blood cells contain membrane proteins that are required to attach to and pass through the blood vessel.

In the end, bone marrow transplants and stem cell transplants are the same. The only difference is where the cells are collected.

If the stem cells are collected from the bone marrow, it is called a Bone Marrow Transplant. If the stem cells are collected from the bloodstream, then the procedure is called Stem Cell Transplant.

Stem cell transplants are more common than bone marrow transplants. This is because:

  • It’s easier to collect stem cells from the bloodstream.
  • A higher amount of cells can be collected from the bloodstream.
  • Blood count recovers quicker after a stem cell transplant.

Treatment methods and type of treatment may differ depending on the kind of pain or disease you have, its intensity, and various cures available for it.

Living with such pains can be challenging and can be a hindrance in daily life.
If you or your loved ones suffer from knee pain then you should consider bone marrow stem cells knee therapy to get rid of the pain.

Stem cell regenerative therapy offers you cutting-edge treatment that can allow you to once again live your life to the fullest. Knee pain must not be ignored. In fact, no pain should be ignored. Get it solved with a bone marrow stem cell treatment from Regen America. With our Stem Cell Regenerative Therapy, you can live the life you want to live again. Check our website to book an appointment, now.

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